The FAS Lab is located in the beautiful city of Lisbon, Portugal. Our antibody engineering research group is affiliated with the Centre for Interdisciplinary Research in Animal Healthy (CIISA) at the Faculty of Veterinary Medicine, University of Lisbon. We apply rational design and molecular evolution approaches – such as in vivo phage display selections, functional screenings and next generation sequencing analysis – to develop future generations of therapeutic antibodies. Based upon this integrated approach, we aim to develop a new generation of “smart bomb antibodies” against challenging targets and unmet diseases. For this purpose, our lab is mainly working with antibody fragments (Fab and scFv) and single-domain antibodies (sdAbs) as therapeutic scaffolds and in the areas of infectious diseases, cancer and neurodegenerative disorders.