Aires da Silva, Aguiar S, Andre S, Oliveira S. Single domain antibodies for brain targeting and drug delivery across the blood-brain barrier. National Patent Application No. 2017/1000081464 (2017).

Aires da Silva F, Corte-Real S; Oliveira S, Gonçalves J. Cell-Based Methods for Coupling Protein Interactions and Binding Molecule Selection and Diversification. International Patent Application No. – PCT/PT2014/000016.

Corte-Real, S., Neves, V., Oliveira, S., Canhao, P., Outeiro, T.,Castanho, M., Aires da Silva, F. and Oliveira S. Antibody Molecules And Peptide Delivery Systems For Use In Alzheimer’s Disease And Related  Disorders. International Patent Application No. PCT/IB2016/050467; WO2016/120843 A1 (2016).

Aires da Silva, F, Corte-Real, S., Canhão, P., Outeiro, T. F. Therapy and Diagnostic for CNS diseases. INPI 20151000008069, January 29, 2015.

Castanho M, Neves V & Aires da Silva F. Design of peptides for brain delivery. National Patent Application No. 20151000007982 (2015)

Aires da Silva F, Corte-Real S; Lourenço S. Modified Albumin-Binding Domains and Uses Thereof to Improve Pharmacokinetics. International Application No. PCT/PT2012/000036; WO/2013/043071 (2012).

Aires da Silva F, Corte-Real S; Gonçalves J. Dual Antigen-Binding Molecules and Uses Thereof. Internation Patent Application. No. 61/771,546, March 1, 2013.

Aires da Silva F, Corte-Real S; Freitas R, Lourenço S. Anti-Tumor Necrosis Factor-Alpha Agents and Uses Thereof. International Application No. PCT/PT2012/000035; WO2013043070A9 (2012).

Aires da Silva F; Lourenço S & Corte-Real S. Selection and Characterization of single domain antibodies againts the HIV-1 gp41 protein and the HR1 domain. National Application (2011).

Gonçalves J & Aires da Silva F,. Engineered rabbit antibody variable domains and uses thereof. International Patent Application No. PCT/PT2008/000018; WO2008136694A9 (2008).